If you've been diagnosed with a scalp condition, your doctor may recommend a scalp biopsy to determine the cause of your symptoms. A scalp biopsy is a procedure in which a small piece of tissue is removed from the scalp for examination. The sample will be examined under a microscope to look for any signs of infection, inflammation, male pattern baldness, autoimmune disease, chronic stress, or cancer. A scalp biopsy for hair loss is a safe and simple procedure that can help your doctor determine the best treatment for your condition. It does not result in any significant discomfort or pain.